MMAE&MMAF Recombinant Monoclonal Antibody

中文名称：

MMAE&MMAF重组抗体
货号：

CSB-RA903890I1m
规格：

￥3000
图片：
The Binding Activity of Disitamab vedotin (Synonyms: RC48) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC₅₀ is 3.523 to 5.356 ng/mL.

The Binding Activity of Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC₅₀ is 3.022 to 4.198 ng/mL.

The Binding Activity of Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) with Anti-MMAE&MMAF antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Disitamab vedotin (Synonyms: RC48) and Depatuxizumab mafodotin (Synonyms: ABT-414) at 2 μg/mL can bind Anti-MMAE&MMAF antibody, the EC₅₀ is 3.523 to 5.356 ng/mL and 3.022 to 4.198 ng/mL, respectively.

The purity of MMAE&MMAF was greater than 95% as determined by SEC-HPLC
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MMAE&MMAF重组单克隆抗体是针对抗体药物偶联物（ADC）中关键细胞毒性成分开发的检测工具，适用于酶联免疫吸附实验（ELISA）平台。该抗体特异性识别单甲基奥瑞他汀E（MMAE）和单甲基奥瑞他汀F（MMAF）两种微管聚合抑制剂，这两种小分子化合物通过破坏微管网络抑制细胞分裂，广泛应用于靶向抗癌药物的开发。经严格验证，该抗体在1:5000至1:50000的宽泛稀释范围内保持稳定检测性能，具备高灵敏度和低交叉反应特性，可精准检测复杂生物样本中MMAE/MMAF的微量存在。其应用场景涵盖ADC药物的体外效价评估、药物偶联效率分析以及药代动力学研究等领域，为科研人员提供可靠的定量检测方案，特别适用于药物开发过程中关键质量属性的监控及作用机制研究，是生物制药领域基础研究的重要工具。
基因名：

MMAE; MMAF
别名：

MMAE, Monomethyl auristatin E, SGD-1010, Vedotin; MMAF, Monomethylauristatin F
反应种属：

Human
免疫原：

MMAE-BSA
标记方式：

Non-conjugated
克隆类型：

Monoclonal
抗体亚型：

IgG2b
纯化方式：

Affinity-chromatography
克隆号：

25G12B5
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
推荐稀释比：

Application Recommended Dilution

ELISA 1:5000-1:50000
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

MMAE&MMAF Recombinant Monoclonal Antibody

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