IL12&IL23 monoclonal antibody

中文名称：

IL12&IL23重组抗体
货号：

CSB-RA011587MA1HU
规格：

￥1320
图片：
The Binding Activity of IL12B&IL12A with Anti-IL12/IL23 monoclonal antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human IL12B&IL12A (CSB-MP4155HU) at 1 μg/mL can bind Anti-IL12/IL23 recombinant antibody, the EC₅₀ is 1.042-1.545 ng/mL.

IHC image of CSB-RA011587MA1HU diluted at 1:50 and staining in paraffin-embedded human lymphnode tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
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CSB-RA011587MA1HU IL12&IL23重组单克隆抗体是针对IL-12和IL-23双靶点设计的高特异性科研工具，适用于ELISA检测。该抗体靶向IL-12（由p35和p40亚基组成）和IL-23（由p19和p40亚基组成），这两种细胞因子通过共享的p40亚基参与免疫调控，能够分别激活Th1和Th17细胞通路，在自身免疫性疾病及炎症反应中发挥关键作用。经ELISA验证，本品可同时识别天然构象下的IL-12和IL-23蛋白，具有高亲和力与低交叉反应性，其重组单克隆特性保障了实验数据的可重复性。科研人员可将其用于体外模型中的细胞因子定量分析、免疫应答机制研究，以及相关药物靶点筛选等基础研究领域，为探索银屑病、炎症性肠病等疾病的病理机制提供可靠工具。本产品严格限于科学研究使用，不涉及任何临床或诊断用途。
Uniprot No.：

P29459&P29460
基因名：

IL12&IL23
别名：

IL12&IL23 monoclonal antibody
反应种属：

Human
免疫原：

Recombinant Human IL12&IL23 protein
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
克隆类型：

Monoclonal
抗体亚型：

hIgG1
纯化方式：

Affinity-chromatography
克隆号：

14D4
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC
推荐稀释比：

Application Recommended Dilution

IHC 1:50-1:200
Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

IL12&IL23 monoclonal antibody

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