GPRC5D Recombinant Monoclonal Antibody

中文名称：

GPRC5D重组抗体
货号：

CSB-RA882153MA01HU
规格：

￥1320
图片：
The Binding Activity of Human GPRC5D with Anti-GPRC5D recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D(CSB-MP882153HU) at 5 μg/mL can bind Anti-GPRC5D recombinant antibody, the EC₅₀ is 8.847-10.38 ng/mL.
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产品描述：

CSB-RA882153MA01HU GPRC5D重组单克隆抗体是针对G蛋白偶联受体C5家族成员D亚型（GPRC5D）开发的高特异性科研工具。该受体作为细胞膜表面重要信号分子，在肿瘤微环境调控及多发性骨髓瘤等疾病中展现出潜在生物学意义。本产品经ELISA平台严格验证，表现出优异的抗原结合能力与低交叉反应性，可精准识别天然及重组形式的目标蛋白。采用重组表达技术制备的抗体具备优异的批次稳定性，为实验数据可重复性提供保障。适用于体外样本中GPRC5D蛋白的定量检测、细胞定位分析及分子互作研究，尤其在肿瘤生物学领域可助力探索受体介导的信号通路机制及其在疾病进展中的作用。科研人员可将其应用于药物靶点验证、肿瘤标志物筛选等基础研究场景，为开发新型治疗策略提供可靠检测手段。该产品仅限于科学研究使用，不适用于临床诊断或其他非科研用途。
Uniprot No.：

Q9NZD1
基因名：

GPRC5D
别名：

GPRC5D; G-protein coupled receptor family C group 5 member D
反应种属：

Human
免疫原：

Recombinant Human GPRC5D protein
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
克隆类型：

Monoclonal
抗体亚型：

hIgG4(S228P)
纯化方式：

Affinity-chromatography
克隆号：

3D4
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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基因功能参考文献：
1. GPRC5D in MM cells makes this gene and its encoded surface protein as promising markers for monitoring the tumor load and hopefully also as targets for antimyeloma antibodies. PMID: 23510526
2. Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma. PMID: 22591013
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 3 family
组织特异性：

Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscl
数据库链接：

HGNC: 13310

OMIM: 607437

KEGG: hsa:55507

STRING: 9606.ENSP00000228887

UniGene: Hs.644599

GPRC5D Recombinant Monoclonal Antibody

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