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ALPG Recombinant Monoclonal Antibody

说明书
  • 中文名称：
    ALPG重组抗体
  • 货号：
    CSB-RA001633MA1HU
  • 规格：
    ￥1320
  • 图片：
    • The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC50 is 14.09-23.17 ng/mL.
    • The Binding Activity of Human ALPP with Anti-ALPP/ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP (CSB-MP001632HU) at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody. The EC50 is 4.478-5.236 ng/mL.
  • 其他：

产品详情

  • 产品描述：
    CSB-RA001633MA1HU是针对ALPG（碱性磷酸酶胎盘型）的重组单克隆抗体，靶向ALPG蛋白的特定表位。ALPG（亦称PLAP）属于碱性磷酸酶家族，主要参与磷酸酯代谢，并在胎盘组织及某些肿瘤细胞中特异性高表达，其表达水平与生殖细胞肿瘤、卵巢癌等疾病的生物学行为相关。本抗体采用重组蛋白免疫技术制备，经ELISA平台严格验证，展现出高特异性和灵敏性，可与天然及重组ALPG蛋白稳定结合，且不同批次间性能高度一致。其应用场景涵盖体外检测实验，包括但不限于ELISA法检测细胞裂解液或血清样本中ALPG的定量分析，适用于生殖生物学、肿瘤标志物筛选及疾病机制研究等领域。该产品经过重组蛋白亲和纯化，确保低内毒素及交叉反应性，为科研人员提供稳定可靠的工具，满足蛋白质功能研究、疾病模型构建及生物标志物开发等需求，所有数据均通过标准化的质控流程验证。
  • Uniprot No.：
    P10696
  • 基因名：
    ALPG
  • 别名：
    ALPG Recombinant Monoclonal Antibody
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ALPG protein
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Monoclonal
  • 抗体亚型：
    hIgG1
  • 纯化方式：
    Affinity-chromatography
  • 克隆号：
    29A5
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
    ELISA Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

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ALPG antibodies

ALPG Proteins

靶点详情

  • 功能：
    Alkaline phosphatase that can hydrolyze various phosphate compounds.
  • 基因功能参考文献：
    1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
    2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
    3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Alkaline phosphatase family
  • 组织特异性：
    Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
  • 数据库链接：

    HGNC: 441

    OMIM: 171810

    KEGG: hsa:251

    STRING: 9606.ENSP00000295453

    UniGene: Hs.333509

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