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oprF Antibody, FITC conjugated

Rare Species
  • 中文名称:
    oprF兔多克隆抗体, FITC偶联
  • 货号:
    CSB-PA318417LC01EZX
  • 规格:
    ¥880
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Pseudomonas aeruginosa oprF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    oprF
  • 别名:
    oprF antibody; PA1777 antibody; Outer membrane porin F antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Pseudomonas aeruginosa
  • 免疫原:
    Recombinant Pseudomonas aeruginosa Outer membrane porin F protein (25-350AA)
  • 免疫原种属:
    Pseudomonas aeruginosa
  • 标记方式:
    FITC
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
  • 基因功能参考文献:
    1. OprF (an outer membrane porin, highly conserved in the Pseudomonas) binds human C3b. PMID: 25964476
    2. LecB binds to the outer membrane protein OprF PMID: 23056489
    3. oprF transcription was increased in response to low NaCl or high sucrose concentrations, and this induced transcription was strongly impaired in the absence of SigX. PMID: 22685281
    4. Prevention of disulfide bond formation in OprF increases its pore-forming activity. PMID: 20978537
    5. This is the first study showing a link between OprF, PQS synthesis, T3SS, and virulence factor production PMID: 21189321
    6. Data show that the recombinant plasmid pIRES-tPA-OprF-MyD88 has been successfully constructed and tPA-OprF and MyD88 protein can be highly expressed in transfected cells. PMID: 19257978
    7. findings suggest that OprF could adopt two alternative conformations in the outer membrane and that folding is thermoregulated PMID: 15528532
    8. findings demonstrate that interferon-gamma binds to an outer membrane protein in Pseudomonas aeruginosa, OprF, resulting in the expression of a quorum-sensing dependent virulence determinant, the PA-I lectin PMID: 16051797
    9. analysis of OprF from Pseudomonas aeruginosa PMID: 16397890
    10. OprF exists in two different conformations PMID: 16595653
    11. analysis of Pseudomonas aeruginosa porin OprF PMID: 16617058
    12. Major outer membrane protein F (OprF) is identified as a protein with important functions; mutant Pseudomonas aeruginosa deficient in OprF negates the antibacterial role of host neutrophil elastase both in vitro and in a pneumonia model. PMID: 18802098

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  • 亚细胞定位:
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族:
    OmpA family
  • 数据库链接:

    KEGG: pae:PA1777

    STRING: 208964.PA1777