cheZ Antibody

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产品详情

产品名称：

Rabbit anti-Escherichia coli (strain K12) cheZ Polyclonal antibody
Uniprot No.：

P0A9H9
基因名：

cheZ
别名：

Protein phosphatase CheZ (EC 3.1.3.-) (Chemotaxis protein CheZ) cheZ b1881 JW1870
宿主：

Rabbit
反应种属：

Escherichia coli (strain K12)
免疫原：

Recombinant Escherichia coli (strain K12) cheZ protein (1-214aa)
免疫原种属：

Escherichia coli (strain K12)
标记方式：

Non-conjugated
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB
推荐稀释比：

Application Recommended Dilution

WB 1:500-1:5000
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
基因功能参考文献：
1. The suitability for FRET analysis as well as functionality of fusions with SNAP- and HaloTag could be demonstrated by studying the transient interaction between chemotaxis response regulator CheY and its phosphatase CheZ PMID: 25856398
2. Amino acid substitutions distant from the active site can affect CheZ catalytic activity and CheYp binding, perhaps via the propagation of structural or dynamic perturbations through a helical bundle. PMID: 21764922
3. simulations suggest that dynamic CheZ localization will sharpen cellular responses to chemoeffectors, increase the range of detectable ligand concentrations, and make adaptation more precise and robust PMID: 16683020
4. Specific CheA-short (CheA(S)) residues, L123 and L126, were identified as critical for CheZ binding. PMID: 19581362
亚细胞定位：

Cytoplasm. Note=Colocalizes with CheA chemoreceptor patches near the cell poles, which requires CheA(short).
蛋白家族：

CheZ family
数据库链接：

KEGG: ecj:JW1870

STRING: 316385.ECDH10B_2022