ZNF410 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZNF410 Polyclonal antibody
Uniprot No.：

Q86VK4
基因名：

ZNF410
别名：

Another partner for ARF 1 antibody; APA 1 antibody; APA1 antibody; Clones 23667 and 23775 zinc finger protein antibody; D12Ertd748e antibody; Zfp410 antibody; Zinc finger protein 410 antibody; Zinc finger protein APA 1 antibody; Zinc finger protein APA-1 antibody; ZN410_HUMAN antibody; Znf410 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Zinc finger protein 410 protein (1-300AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3' in regulatory elements and modulates transcription of target genes. Indirectly represses transcription of HBG1 and HBG2, hemoglobin subunits gamma-1 and gamma-2, in erythroid cells, via direct transcriptional activation of the chromodomain protein CHD4, a component of the NuRD complex. Activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. Activates transcription of the gap junction gene GJC1, perhaps in response to increasing glucose.
基因功能参考文献：
1. No association was found between Apa1 genotypes and osteoporosis PMID: 26290023
2. APA1 has a role in inducing extracellular matrix remodeling genes PMID: 12370286
3. VDR polymorphism genotypes and haplotypes did not directly alter recurrence risk, but the reduction in risk associated with high dairy product intake was confined to individuals with ApaI aA/AA genotype. PMID: 18470879
亚细胞定位：

Nucleus.
组织特异性：

Widely expressed.
数据库链接：

HGNC: 20144

KEGG: hsa:57862

STRING: 9606.ENSP00000407130

UniGene: Hs.270869