ZNF274 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZNF274 Polyclonal antibody
Uniprot No.：

Q96GC6
基因名：

ZNF274
别名：

ZNF274 antibody; ZKSCAN19 antibody; SP2114Neurotrophin receptor-interacting factor homolog antibody; Zinc finger protein 274 antibody; Zinc finger protein HFB101 antibody; Zinc finger protein with KRAB and SCAN domains 19 antibody; Zinc finger protein zfp2 antibody; Zf2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
基因功能参考文献：
1. A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain. PMID: 24128372
亚细胞定位：

Cytoplasm. Nucleus, nucleolus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
数据库链接：

HGNC: 13068

OMIM: 605467

KEGG: hsa:10782

STRING: 9606.ENSP00000321209

UniGene: Hs.83761