ZNF175 Antibody

中文名称：

ZNF175兔多克隆抗体
货号：

CSB-PA026556LA01HU
规格：

￥440
图片：
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026556LA01HU at dilution of 1:100
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZNF175 Polyclonal antibody
Uniprot No.：

Q9Y473
基因名：

ZNF175
别名：

OTK18 antibody; Zinc finger protein 175 antibody; Zinc finger protein OTK18 antibody; ZN175_HUMAN antibody; ZNF175 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Zinc finger protein 175 protein (1-711AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，ZNF175 Antibody (CSB-PA026556LA01HU)，的标记方式是Non-conjugated。对于ZNF175 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA026556LB01HU	ZNF175 Antibody, HRP conjugated	ELISA
FITC	CSB-PA026556LC01HU	ZNF175 Antibody, FITC conjugated
Biotin	CSB-PA026556LD01HU	ZNF175 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC
推荐稀释比：

Application Recommended Dilution

IHC 1:20-1:200
Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
基因功能参考文献：
1. Transcriptional suppressor OTK18 plays a role in macrophage control of viral replication during advanced HIV-1 infection. PMID: 14688346
2. OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. PMID: 15081264
3. Plasma OTK18 levels are positively correlated to CD8 T-cell counts, independent of HIV-1 status. PMID: 18773297
4. These results suggest a role for OTK18 in innate immunity. PMID: 18776638
5. These data suggest that calpain and proteasome are involved in OTK18 endoproteolysis and degradation PMID: 19034669
6. HIV-1 induces OTK18 expression through a YIN-YANG-1 mediated manner in human macrophages PMID: 19034670
7. OTK18 may play a role in neurotrophin production and consequently support neuronal survival. PMID: 19247725
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亚细胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
组织特异性：

Ubiquitous.
数据库链接：

HGNC: 12964

OMIM: 601139

KEGG: hsa:7728

STRING: 9606.ENSP00000262259

UniGene: Hs.119014