ZFR Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZFR Polyclonal antibody
Uniprot No.：

Q96KR1
基因名：

ZFR
别名：

FLJ41312 antibody; hZFR antibody; M phase phosphoprotein homolog antibody; M-phase phosphoprotein homolog antibody; zfr antibody; ZFR_HUMAN antibody; zinc finger RNA binding protein antibody; Zinc finger RNA-binding protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Zinc finger RNA-binding protein (150-268AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.
基因功能参考文献：
1. ZFR expression is tightly controlled during macrophage development; monocytes express truncated ZFR isoforms, while macrophages induce full-length ZFR to modulate macrophage-specific alternative splicing. PMID: 29559679
2. Identified a new circRNA, circZFR, that was significantly upregulated in papillary thyroid carcinoma (PTC). CircZFR could promote C8orf4 expression via serving as a competing endogenous RNA of miR-1261 in PTC cells. Rescue assays indicated that restoration of C8orf4 significantly attenuated the inhibitory effects of circZFR knockdown on PTC cell proliferation, migration and invasion. PMID: 29842886
3. polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR PMID: 25799583
亚细胞定位：

Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome.
组织特异性：

Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.
数据库链接：

HGNC: 17277

OMIM: 615635

KEGG: hsa:51663

STRING: 9606.ENSP00000265069

UniGene: Hs.435231