ZFAND6 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZFAND6 Polyclonal antibody
Uniprot No.：

Q6FIF0
基因名：

ZFAND6
别名：

ZFAND6 antibody; AWP1 antibody; ZA20D3 antibody; HT032 antibody; AN1-type zinc finger protein 6 antibody; Associated with PRK1 protein antibody; Zinc finger A20 domain-containing protein 3 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human AN1-type zinc finger protein 6 protein (1-208AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes.
基因功能参考文献：
1. ZFAND6 was identified as a type 2 diabetes susceptibility gene. ZFAND6 plays a role in insulin secretion in vitro. PMID: 28580277
2. By observing the data obtained from the isothermal titration calorimetry assay, both of the human proteins (KRCC1 and ZFAND6) were demonstrated to bind to their respective Toxoplasma gondii SAG1 and SAG2 proteins. PMID: 29351065
3. The AN1 domain of AWP1 mediated the functional interaction with tumor necrosis factor receptor-associated factor 2, and the A20 domain was responsible for the negative regulation of nuclear factor kappaB activation. PMID: 21810480
亚细胞定位：

Cytoplasm.
组织特异性：

Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta.
数据库链接：

HGNC: 30164

OMIM: 610183

KEGG: hsa:54469

STRING: 9606.ENSP00000261749

UniGene: Hs.596679