ZC4H2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZC4H2 Polyclonal antibody
Uniprot No.：

Q9NQZ6
基因名：

ZC4H2
别名：

HCA127 antibody; Hepatocellular carcinoma-associated antigen 127 antibody; KIAA1166 antibody; OTTHUMP00000023432 antibody; Zc4h2 antibody; ZC4H2_HUMAN antibody; Zinc finger C4H2 domain containing antibody; Zinc finger C4H2 domain-containing protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Zinc finger C4H2 domain-containing protein (1-224AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
基因功能参考文献：
1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
2. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
3. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388
相关疾病：

Wieacker-Wolf syndrome (WRWF)
亚细胞定位：

Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.
组织特异性：

Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.
数据库链接：

HGNC: 24931

OMIM: 300897

KEGG: hsa:55906

STRING: 9606.ENSP00000363972

UniGene: Hs.28249