ZBTB8OS Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) ZBTB8OS Polyclonal antibody
Uniprot No.：

Q8IWT0
基因名：

ZBTB8OS
别名：

ARCH antibody; ARCH_HUMAN antibody; ARCH2 antibody; Archease (ARCH) antibody; Archease like protein antibody; MGC62007 antibody; OTTHUMP00000036124 antibody; Protein archease antibody; Protein ZBTB8OS antibody; ZBTB8OS antibody; Zinc finger and BTB domain containing 8 opposite strand antibody; Zinc finger and BTB domain containing opposite strand protein 8 antibody; Zinc finger and BTB domain-containing opposite strand protein 8 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein archease protein (2-136AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
基因功能参考文献：
1. ARCH mutation is associated with chronic myelomonocytic leukemia. PMID: 26648538
2. RTCB, the catalytic subunit of the tRNA ligase complex, and its co-factor archease mediate XBP1 mRNA splicing both in vitro and in vivo. PMID: 25378478
3. archease (also called ZBTB8OS), a protein of unknown function, is required for full activity of the human tRNA ligase complex and, in cooperation with DDX1, facilitates the formation of an RTCB-guanylate intermediate central to mammalian RNA ligation PMID: 24870230
蛋白家族：

Archease family
数据库链接：

HGNC: 24094

KEGG: hsa:339487

STRING: 9606.ENSP00000417677

UniGene: Hs.655921