YIPF3 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) YIPF3 Polyclonal antibody
Uniprot No.：

Q9GZM5
基因名：

YIPF3
别名：

YIPF3; C6orf109; KLIP1; Protein YIPF3; Killer lineage protein 1; Natural killer cell-specific antigen KLIP1; YIP1 family member 3
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein YIPF3 protein (2-148AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
基因功能参考文献：
1. The significance of YIPF3 protein for the maintenance of the morphology of the Golgi was tested by RNA interference, revealing a number of specific morphological changes to this organelle on their depletion. PMID: 27999994
2. Knockdown of YIPF1 and YIPF2, but not that of YIPF6, also reduced intracellular glycans in HT-29 cells. Thus, we confirmed that YIPF1, YIPF2, and YIPF6 play a significant role in supporting normal glycan synthesis PMID: 28286305
3. YIPF3 is synthesized in the ER as a N-glycosylated form (40 kDa), is then O-glycosylated in the Golgi apparatus to become a lower mobility form (46 kDa) and finally becomes a higher mobility form cleaved at its C-terminal luminal domain (36 kDa). PMID: 21757827
4. identification and characterization of KLIP-1, a novel transmembrane protein whose expression correlates with hematopoietic activity PMID: 12490290
亚细胞定位：

Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated.
蛋白家族：

YIP1 family
组织特异性：

Expressed by nucleated hematopoietic cells (at protein level).
数据库链接：

HGNC: 21023

OMIM: 609775

KEGG: hsa:25844

STRING: 9606.ENSP00000361499

UniGene: Hs.440950