WDR60 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) WDR60 Polyclonal antibody
Uniprot No.：

Q8WVS4
基因名：

WDR60
别名：

WDR60WD repeat-containing protein 60 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human WD repeat-containing protein 60 protein (1-200AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. Requires also to maintain a functional transition zone.
基因功能参考文献：
1. exome analysis allowed to identify mutations not previously reported in the DYNC2H1 (MIM 603297) and WDR60 (MIM 615462) genes, both codifying for ciliary intraflagellar transport components whose mutations are known to cause Jeune syndrome PMID: 26874042
2. These findings show that WDR60 mutations can cause skeletal ciliopathies and suggest a role for WDR60 in ciliogenesis. PMID: 23910462
相关疾病：

Short-rib thoracic dysplasia 8 with or without polydactyly (SRTD8)
亚细胞定位：

Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
组织特异性：

Expressed in chondrocytes (at protein level).
数据库链接：

HGNC: 21862

OMIM: 615462

KEGG: hsa:55112

STRING: 9606.ENSP00000384290

UniGene: Hs.389945