VKORC1L1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) VKORC1L1 Polyclonal antibody
Uniprot No.：

Q8N0U8
基因名：

VKORC1L1
别名：

VKORC1L1; Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.
基因功能参考文献：
1. This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. PMID: 29054760
2. a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration PMID: 24532791
3. VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival. PMID: 21367861
4. VKORC1L1 does not affect the variability of warfarin dose requirement in a Japanese patient population PMID: 17996924
亚细胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

VKOR family
数据库链接：

HGNC: 21492

OMIM: 608838

KEGG: hsa:154807

STRING: 9606.ENSP00000353998

UniGene: Hs.427232