VASN Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) VASN Polyclonal antibody
Uniprot No.：

Q6EMK4
基因名：

VASN
别名：

2610528G05Rik antibody; PRO1282 antibody; PRO357 antibody; Protein slit-like 2 antibody; Slit like 2 antibody; Slitl2 antibody; UNQ314 antibody; Vasn antibody; VASN_HUMAN antibody; Vasorin antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Peptide sequence from Human Vasorin protein (553-572AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May act as an inhibitor of TGF-beta signaling.
基因功能参考文献：
1. confirmed for the first time that HepG2-derived VASN can be transferred to human umbilical vein endothelial cells (HUVECs) via receptor mediated endocytosis of exosomes, at least in part through HSPGs PMID: 26157350
2. results suggest that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall [vasorin] PMID: 15247411
亚细胞定位：

Membrane; Single-pass type I membrane protein. Secreted.
组织特异性：

Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending ao
数据库链接：

HGNC: 18517

OMIM: 608843

KEGG: hsa:114990

STRING: 9606.ENSP00000306864

UniGene: Hs.372579