USP45 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) USP45 Polyclonal antibody
Uniprot No.：

Q70EL2
基因名：

USP45
别名：

USP45 antibody; Ubiquitin carboxyl-terminal hydrolase 45 antibody; EC 3.4.19.12 antibody; Deubiquitinating enzyme 45 antibody; Ubiquitin thioesterase 45 antibody; Ubiquitin-specific-processing protease 45 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration.
基因功能参考文献：
1. these results establish USP45 as a new regulator of XPF-ERCC1 crucial for efficient DNA repair PMID: 25538220
亚细胞定位：

Photoreceptor inner segment. Cytoplasm. Nucleus.
蛋白家族：

Peptidase C19 family
组织特异性：

Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
数据库链接：

HGNC: 20080

KEGG: hsa:85015

STRING: 9606.ENSP00000333376

UniGene: Hs.143410