UNC45B Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) UNC45B Polyclonal antibody
Uniprot No.：

Q8IWX7
基因名：

UNC45B
别名：

Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein unc-45 homolog B protein (602-710AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
基因功能参考文献：
1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
相关疾病：

Cataract 43 (CTRCT43)
亚细胞定位：

Cytoplasm, cytosol.
组织特异性：

Expressed in eye lens tissues.
数据库链接：

HGNC: 14304

OMIM: 611220

KEGG: hsa:146862

STRING: 9606.ENSP00000268876

UniGene: Hs.379636