TXNRD3 Antibody

产品详情

Uniprot No.：

Q86VQ6
基因名：

TXNRD3
别名：

TGR antibody; Thioredoxin and glutathione reductase antibody; Thioredoxin glutathione reductase antibody; Thioredoxin reductase 2 antibody; Thioredoxin reductase 3 antibody; Thioredoxin reductase TR2 antibody; TR2 antibody; TRXR3 antibody; TRXR3_HUMAN antibody; TXNRD3 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Human TXNRD3
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
基因功能参考文献：
1. Findings represent the first characterization of hTGR and provide new insights into the reaction mechanism and the regulation of monothiol Grx-containing thioredoxin glutathione reductases. PMID: 29222842
2. A role of GPx2, TrxR2 and TrxR3 in proliferation, apoptosis and, therefore, also during cancer development. PMID: 22683372
3. This study pertains to use of non-AUG (CUG) start codon in mouse thioredoxin reductase 3 gene, and conservation of this site in other mammals. PMID: 20018845
亚细胞定位：

Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum.
蛋白家族：

Class-I pyridine nucleotide-disulfide oxidoreductase family
数据库链接：

HGNC: 20667

OMIM: 606235

KEGG: hsa:114112

STRING: 9606.ENSP00000430031

UniGene: Hs.477475