TXNL4A Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TXNL4A Polyclonal antibody
Uniprot No.：

P83876
基因名：

TXNL4A
别名：

TXNL4A antibody; DIM1 antibody; TXNL4Thioredoxin-like protein 4A antibody; DIM1 protein homolog antibody; Spliceosomal U5 snRNP-specific 15 kDa protein antibody; Thioredoxin-like U5 snRNP protein U5-15kD antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Thioredoxin-like protein 4A protein (1-142AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
基因功能参考文献：
1. Recessive variants in TXNL4A were identified in two individuals with Burn-McKeown syndrome as well as in three individuals (from two families) with isolated choanal atresia. PMID: 28905882
2. Reporter gene and in vivo assays showed that the promoter deletions led to reduced expression of TXNL4A. Depletion of TXNL4A (Dib1) in yeast demonstrated reduced assembly of the tri-snRNP complex. PMID: 25434003
3. human dim1 is a peptidase with autocleavage activity that results in a thioredoxin-like core PMID: 17177886
相关疾病：

Burn-McKeown syndrome (BMKS)
亚细胞定位：

Nucleus.
蛋白家族：

DIM1 family
数据库链接：

HGNC: 30551

OMIM: 608572

KEGG: hsa:10907

STRING: 9606.ENSP00000269601

UniGene: Hs.465498