TTYH2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TTYH2 Polyclonal antibody
Uniprot No.：

Q9BSA4
基因名：

TTYH2
别名：

TTYH2; C17orf29; Protein tweety homolog 2; hTTY2
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein tweety homolog 2 protein (455-534AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
基因功能参考文献：
1. TTYH2 gene expression is significantly up-regulated in colon cancer. The TTYH2 gene may play an important role in regulating both proliferating and metastatic potentials of colorectal cancer. PMID: 17569141
2. N-glycosylation is not the determining factor for TTYH2 trafficking to the plasma membrane. PMID: 18260827
3. expressed most highly in brain and testis and at lower levels in heart, ovary, spleen, and peripheral blood leukocytes. Expression of this gene is upregulated in 13 of 16 (81%) renal cell carcinoma samples examined PMID: 11597145
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Tweety family
组织特异性：

Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma.
数据库链接：

HGNC: 13877

OMIM: 608855

KEGG: hsa:94015

STRING: 9606.ENSP00000269346

UniGene: Hs.27935