TTF1 Antibody, FITC conjugated
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中文名称:TTF1兔多克隆抗体, FITC偶联
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货号:CSB-PA11677C0Rb
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规格:¥880
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) TTF1 Polyclonal antibody
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Uniprot No.:
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基因名:
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别名:RNA polymerase I termination factor antibody; Transcription termination factor 1 antibody; Transcription termination factor I antibody; Transcription termination factor RNA polymerase I antibody; TTF 1 antibody; TTF-1 antibody; TTF-I antibody; Ttf1 antibody; TTF1_HUMAN antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Transcription termination factor 1 protein (12-232AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:FITC
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相关产品
靶点详情
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功能:Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
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基因功能参考文献:
- the TTF-1 protein and mRNA are specifically expressed in schwannomas PMID: 29104109
- Human TTF-I localizes in the nucleolus and N-terminus (1-224) of hTTF-I which include nucleolus localization sequence and the expression of Human TTF-I 521-732 increased HIV-I production by regulating transactivation of the LTR promoter. PMID: 29555014
- These findings collectively suggest that the triple combination of survivin knockdown with ABT-263 and trametinib treatment, may be a potential strategy for the treatment of KRAS-mutant lung adenocarcinoma. Furthermore, our findings indicate that the welldifferentiated type of KRAS-mutant lung tumors depends, at least in part, on TTF1 for growth. PMID: 29658609
- TTF-1 expression may serve as a predictive marker to identify lung cancer patients who may benefit from the addition of bevacizumab to platinum doublet therapy. PMID: 30194207
- Our results showed that an approach of using only a two-antibody panel (p40 and TTF-1) might help in reduction of diagnostic category of NSCLC-NOS significantly and contribute in saving tissue for future molecular testing PMID: 29168459
- Single nucleotide polymorphism in TTF1 gene is associated with Systemic lupus erythematosus PMID: 28246883
- Case Report: KRAS mutation-positive bronchial surface epithelium type lung adenocarcinoma with strong expression of TTF-1. PMID: 26823891
- Overexpression of Transcription Termination Factor 1 is Associated with Colorectal Cancer PMID: 26036188
- Depletion of TTF-I recapitulates the effects of ARF on ribosomal RNA synthesis and is rescued by the introduction of a TTF-I transgene. PMID: 20513429
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亚细胞定位:Nucleus. Nucleus, nucleolus.
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数据库链接:
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