TTC5 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TTC5 Polyclonal antibody
Uniprot No.：

Q8N0Z6
基因名：

TTC5
别名：

TTC5Tetratricopeptide repeat protein 5 antibody; TPR repeat protein 5 antibody; Stress-responsive activator of p300 antibody; Strap antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
基因功能参考文献：
1. Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. PMID: 24091941
2. TTC5 and EP300 cooperate to prevent excessive accumulation of MYC in AML cells and their sensitization to cell death. PMID: 23559008
3. TTC5 is a novel cofactor regulating GR function in a stress-dependent manner. PMID: 21147850
亚细胞定位：

Nucleus. Cytoplasm.
数据库链接：

HGNC: 19274

KEGG: hsa:91875

STRING: 9606.ENSP00000258821

UniGene: Hs.98553