TSPAN5 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TSPAN5 Polyclonal antibody
Uniprot No.：

P62079
基因名：

TSPAN5
别名：

TSPAN5; TM4SF9; Tetraspanin-5; Tspan-5; Tetraspan NET-4; Transmembrane 4 superfamily member 9
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Tetraspanin-5 protein (114-232AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulates ADAM10 maturation and trafficking to the cell surface. Promotes ADAM10-mediated cleavage of CD44.
基因功能参考文献：
1. intensity in villi in tubal pregnancy was significantly higher than that in normal intrauterine pregnancy PMID: 29908376
2. Tspan5 may serve as a prognostic biomarker for predicting outcome of gastric cancer patients. Tspan5 functions as a tumour suppressor in stomach to control the tumour growth. PMID: 27223087
3. Endothelial Tspan5- and Tspan17-ADAM10 complexes may regulate inflammation by maintaining normal VE-cadherin expression and promoting T lymphocyte transmigration. PMID: 28600292
4. two TspanC8-specific motifs in the large extracellular domain of Tspan5 that are important for ADAM10 interaction and exit from the endoplasmic reticulum. One of the anti-Tspan5 mAbs does not recognize Tspan5 associated with ADAM10, providing a convenient way to measure the fraction of Tspan5 not associated with ADAM10. PMID: 28428248
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Tetraspanin (TM4SF) family
数据库链接：

HGNC: 17753

OMIM: 613136

KEGG: hsa:10098

STRING: 9606.ENSP00000307701

UniGene: Hs.118118