TRAT1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TRAT1 Polyclonal antibody
Uniprot No.：

Q6PIZ9
基因名：

TRAT1
别名：

HSPC062 antibody; pp29/30 antibody; T cell receptor interacting molecule antibody; T-cell receptor-associated transmembrane adapter 1 antibody; T-cell receptor-interacting molecule antibody; TCRIM antibody; TRAT1 antibody; TRAT1_HUMAN antibody; TRIM antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human T-cell receptor-associated transmembrane adapter 1 protein (29-186AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
基因功能参考文献：
1. TRIM proteins trim the balance of homoeostasis by modulating various biological pathways through protein-protein interactions. PMID: 23969027
2. MG53/TRIM72 protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types. PMID: 23699904
3. TRIM acts to chaperone CTLA-4 transport to the cell surface; this function would be required to account for the phenotypic and functional properties of CD8(+) Tregs. PMID: 18817831
亚细胞定位：

Cell membrane; Single-pass type III membrane protein.
组织特异性：

Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
数据库链接：

HGNC: 30698

OMIM: 604962

KEGG: hsa:50852

STRING: 9606.ENSP00000295756

UniGene: Hs.138701