TNP2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TNP2 Polyclonal antibody
Uniprot No.：

Q05952
基因名：

TNP2
别名：

TNP2 antibody; Nuclear transition protein 2 antibody; TP-2 antibody; TP2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Nuclear transition protein 2 protein (1-138AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
基因功能参考文献：
1. the quantity of PRM1, PRM2, and TNP2 transcripts and the PRM1/PRM2 mRNA ratio affect spermiogenesis, sperm morphology PMID: 25536093
2. MiR-122 may influence spermatozoa-like cells by suppressing TNP2 expression and inhibiting the expression of proteins associated with sperm development. PMID: 23327642
3. analysis of the TNP2 gene did not show any association with infertility. PMID: 20522125
4. Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3. PMID: 19710011
亚细胞定位：

Nucleus. Chromosome.
蛋白家族：

Nuclear transition protein 2 family
组织特异性：

Expressed by spermatids (at protein level).
数据库链接：

HGNC: 11952

OMIM: 190232

KEGG: hsa:7142

STRING: 9606.ENSP00000325738

UniGene: Hs.513349