TMEM14A Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TMEM14A Polyclonal antibody
Uniprot No.：

Q9Y6G1
基因名：

TMEM14A
别名：

TMEM14A; C6orf73; PTD011; Transmembrane protein 14A
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Transmembrane protein 14A protein (45-78AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
基因功能参考文献：
1. these results indicate that TMEM14A has a pro-tumorigenic effect in ovarian cancer cells, suggesting an important role of this protein in ovarian cancer oncogenesis and metastasis. PMID: 26896463
2. findings show for the first time that TMEM14A inhibits apoptosis by blocking the mitochondrial permeability transition and stabilizing mitochondrial membrane potential PMID: 21723035
亚细胞定位：

Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
蛋白家族：

TMEM14 family
组织特异性：

Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level).
数据库链接：

HGNC: 21076

KEGG: hsa:28978

UniGene: Hs.94896