TIMMDC1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TIMMDC1 Polyclonal antibody
Uniprot No.：

Q9NPL8
基因名：

TIMMDC1
别名：

TIMMDC1; C3orf1; UNQ247/PRO284; Complex I assembly factor TIMMDC1, mitochondrial; Protein M5-14; Translocase of inner mitochondrial membrane domain-containing protein 1; TIMM domain containing-protein 1
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.
基因功能参考文献：
1. Cell-cycle arrest genes such as CCNG2 and PTEN as well as genes involved in cell migration inhibition, such as TIMP3 and COL3A1, were upregulated after C3orf1 depletion in 95D cells. PMID: 25391042
2. Quantitative proteomics demonstrated a role for TIMMDC1 in assembly of membrane-embedded and soluble arms of the complex. PMID: 24344204
亚细胞定位：

Mitochondrion membrane; Multi-pass membrane protein.
蛋白家族：

Tim17/Tim22/Tim23 family
组织特异性：

Generalized expression enhanced in heart and skeletal muscle.
数据库链接：

HGNC: 1321

OMIM: 615534

KEGG: hsa:51300

STRING: 9606.ENSP00000418803

UniGene: Hs.477287