TFPT Antibody

产品详情

Uniprot No.：

P0C1Z6
基因名：

TFPT
别名：

Amida antibody; INO80 complex subunit F antibody; INO80F antibody; Protein FB1 antibody; TCF3 (E2A) fusion partner (in childhood Leukemia) antibody; TCF3 fusion partner antibody; TFPT antibody; TFPT_HUMAN antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human TFPT
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Appears to promote apoptosis in a p53/TP53-independent manner.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
基因功能参考文献：
1. TCF3/E2A is Conserved Specific Coregulators of the p21:PUMA Expression Ratio. PMID: 23684607
2. Although p53 is a main regulator of apoptosis in mammalian cells, the Tfpt induced apoptosis appears p53-independent. PMID: 17041757
3. FB1 is an important binding partner and a functional regulator of U19/EAF2, EAF1, and/or ELL. PMID: 17395368
相关疾病：

A chromosomal aberration involving TFPT is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Inversion inv(19)(p13;q13) with TCF3.
亚细胞定位：

Nucleus.
数据库链接：

HGNC: 13630

OMIM: 609519

KEGG: hsa:29844

STRING: 9606.ENSP00000375639

UniGene: Hs.590939