TFEC Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TFEC Polyclonal antibody
Uniprot No.：

O14948
基因名：

TFEC
别名：

bHLHe34 antibody; Class E basic helix-loop-helix protein 34 antibody; hTFEC-L antibody; TCFEC antibody; TFE-C antibody; Tfec antibody; TFEC protein antibody; TFEC_HUMAN antibody; TFECL antibody; Transcription factor EC antibody; Transcription factor EC-like antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Transcription factor EC protein (1-197AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
基因功能参考文献：
1. Two alternatively spliced TFEC isoforms have been found to be sequence-specific transcriptional activators of the nonmuscle myosin II heavy chain-A gene in transfected cells. PMID: 11467950
亚细胞定位：

Nucleus.
蛋白家族：

MiT/TFE family
组织特异性：

Expressed moderately in spleen, kidney, bone marrow, small intestine and leukocytes. Expressed weakly in testis, trachea and colon.
数据库链接：

HGNC: 11754

OMIM: 604732

KEGG: hsa:22797

STRING: 9606.ENSP00000265440

UniGene: Hs.125962