TAF2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TAF2 Polyclonal antibody
Uniprot No.：

Q6P1X5
基因名：

TAF2
别名：

TAF2 antibody; CIF150 antibody; TAF2B antibody; Transcription initiation factor TFIID subunit 2 antibody; 150 kDa cofactor of initiator function antibody; RNA polymerase II TBP-associated factor subunit B antibody; TBP-associated factor 150 kDa antibody; Transcription initiation factor TFIID 150 kDa subunit antibody; TAF(II)150 antibody; TAFII-150 antibody; TAFII150 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Transcription initiation factor TFIID subunit 2 protein (400-450AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.
基因功能参考文献：
1. the TAF2-TAF8-TAF10 complex demonstrates that there is a stepwise assembly pathway of nuclear holo-TFIID, regulated by nuclear import of preformed cytoplasmic submodules PMID: 25586196
2. This study suggested that the Microcephaly thin corpus callosum intellectual disability syndrome is caused by the more conserved mutation p.Thr186Arg, with the second sequence change identified, p.Pro416His. PMID: 24084144
相关疾病：

Mental retardation, autosomal recessive 40 (MRT40)
亚细胞定位：

Nucleus.
蛋白家族：

TAF2 family
组织特异性：

Expressed in all tissues tested.
数据库链接：

HGNC: 11536

OMIM: 604912

KEGG: hsa:6873

STRING: 9606.ENSP00000367406

UniGene: Hs.122752