SUSD6 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SUSD6 Polyclonal antibody
Uniprot No.：

Q92537
基因名：

SUSD6
别名：

SUSD6 antibody; DRAGO antibody; KIAA0247 antibody; Sushi domain-containing protein 6 antibody; Drug-activated gene overexpressed protein antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Sushi domain-containing protein 6 protein (144-303AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play a role in growth-suppressive activity and cell death. May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium. Plays a role in preventing tumor onset.
基因功能参考文献：
1. KIAA0247 is a candidate prognostic biomarker and potential therapeutic target in NSCLC. PMID: 29451718
2. overexpression of KIAA0247 is able to inhibit phosphorylation of AKT and Stat3 in glioma cells, resulting in inactivation of the AKT and Stat3 signaling pathways, this ultimately decreases the expression of PCNA, CyclinD1, Bcl2 and VEGF. PMID: 27893430
3. DRAGO (drug-activated gene overexpressed) KIAA0247 represents a new p53-dependent gene highly regulated in human cells and whose expression cooperates with p53 in tumor suppressor functions. PMID: 24652652
4. This is the first description of a linkage between KIAA0247 and colorectal cancer. PMID: 21619678
5. gene silencing in umbilical vein endothelial cells causes decrease in monocyte chemoattractant protein-1 production during endotoxemia PMID: 20236627
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亚细胞定位：

Membrane; Single-pass type I membrane protein.
数据库链接：

HGNC: 19956

KEGG: hsa:9766

UniGene: Hs.440025