ST3GAL6 Antibody

产品详情

Uniprot No.：

Q9Y274
基因名：

ST3GAL6
别名：

ibody; 3-sialyltransferase VI antibody; alpha-2,3-sialyltransferase VI antibody; alpha2,3-sialyltransferase antibody; CMP-NeuAc:beta-galactoside alpha-2 antibody; CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI antibody; SIA10_HUMAN antibody; Sialyltransferase 10 antibody; ST3Gal VI antibody; ST3GAL6 antibody; ST3GalVI antibody; Type 2 lactosamine alpha-2,3-sialyltransferase antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human ST3GAL6
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
基因功能参考文献：
1. The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. PMID: 25061176
2. the occurrence of CD75s- and iso-CD75s-gangliosides in tumor tissues is largely independent of the transcriptional expression of ST6GAL1 and ST3GAL6 PMID: 21147760
3. Expression of ST3Gal IV in several gastrointestinal cell lines is correlated with the expression of sialyl Lewis x at the cell surface. PMID: 19781661
4. Epigenetic changes in a group of glycosyltransferases including B4GALNT2 and ST3GAL6 represent a malignant phenotype of gastric cancer caused by silencing of the activity of these enzymes PMID: 18485915
亚细胞定位：

Golgi apparatus membrane; Single-pass type II membrane protein.
蛋白家族：

Glycosyltransferase 29 family
组织特异性：

Ubiquitous.
数据库链接：

HGNC: 18080

OMIM: 607156

KEGG: hsa:10402

STRING: 9606.ENSP00000377717

UniGene: Hs.148716