SRP54 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SRP54 Polyclonal antibody
Uniprot No.：

P61011
基因名：

SRP54
别名：

Signal recognition particle 54 kDa protein antibody; Signal recognition particle 54kDa antibody; SRP 54 antibody; SRP54 antibody; SRP54_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Signal recognition particle 54 kDa protein (1-504AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
基因功能参考文献：
1. autosomal dominant mutations in SRP54, a key member of the cotranslation protein-targeting pathway, lead to syndromic neutropenia with a Shwachman-Diamond-like phenotype. PMID: 28972538
亚细胞定位：

Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
蛋白家族：

GTP-binding SRP family, SRP54 subfamily
数据库链接：

HGNC: 11301

OMIM: 604857

KEGG: hsa:6729

STRING: 9606.ENSP00000216774

UniGene: Hs.167535