SPIRE2 Antibody

产品详情

Uniprot No.：

Q8WWL2
基因名：

SPIRE2
别名：

MGC117166 antibody; Protein spire homolog 2 antibody; Spir-2 antibody; SPIR2_HUMAN antibody; Spire homolog 2 (Drosophila) antibody; SPIRE2 antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human SPIRE2
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis. Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage.
基因功能参考文献：
1. influences intracellular replication of Salmonella typhimurium PMID: 27627128
亚细胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
蛋白家族：

Spire family
数据库链接：

HGNC: 30623

OMIM: 609217

KEGG: hsa:84501

STRING: 9606.ENSP00000367494

UniGene: Hs.461786