SLC25A37 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SLC25A37 Polyclonal antibody
Uniprot No.：

Q9NYZ2
基因名：

SLC25A37
别名：

SLC25A37; MFRN; MSCP; HT015; Mitoferrin-1; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Solute carrier family 25 member 37
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Mitoferrin-1 protein (1-44AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
基因功能参考文献：
1. The findings of this study implicate that the SCL25A37 is a major depressive disorder susceptibility gene whose expression may influence major depressive disorder risk. PMID: 27643475
2. Data show that abnormal MFRN1 expression can contribute to erythropoietic protoporphyria phenotype in some patients, probably by causing a reduction in FECH activity. PMID: 21627978
3. hypoxia induces the expression of mitoferrin mRNAs through separate mechanisms in erythroid cells PMID: 19187226
亚细胞定位：

Mitochondrion inner membrane; Multi-pass membrane protein.
蛋白家族：

Mitochondrial carrier (TC 2.A.29) family
数据库链接：

HGNC: 29786

OMIM: 610387

KEGG: hsa:51312

STRING: 9606.ENSP00000429200

UniGene: Hs.596025