SLC16A10 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SLC16A10 Polyclonal antibody
Uniprot No.：

Q8TF71
基因名：

SLC16A10
别名：

SLC16A10 antibody; MCT10 antibody; TAT1 antibody; Monocarboxylate transporter 10 antibody; MCT 10 antibody; Aromatic amino acid transporter 1 antibody; Solute carrier family 16 member 10 antibody; T-type amino acid transporter 1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Monocarboxylate transporter 10 protein (159-201AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sodium-independent transporter that mediates the uptake of aromatic acids. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells.
基因功能参考文献：
1. In the MCT10 modeled structure, N81 appeared to protrude into the putative trajectory of tryptophan. PMID: 28754537
2. the aim of this study was to examine if MCT8 and MCT10 increase the availability of triiodothyronine for its nuclear receptor. PMID: 27492966
3. High TAT1 expression is associated with metastasis and recurrence in endometrial cancer. PMID: 26779635
4. monocarboxylate transporter 10 facilitates bromoacetyl [(125)I] iodothyronine transport, but is not labeled by it PMID: 21315799
5. Increased MCT8 and decreased MCT10 expression within placentae of pregnancies complicated by IUGR may contribute to aberrant development of the fetoplacental unit. PMID: 20167367
6. MCT10 is at least as active a thyroid hormone transporter as hMCT8, and that both transporters facilitate iodothyronine uptake as well as efflux. PMID: 18337592
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亚细胞定位：

Cell membrane; Multi-pass membrane protein. Basolateral cell membrane.
蛋白家族：

Major facilitator superfamily, Monocarboxylate porter (TC 2.A.1.13) family
组织特异性：

Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart.
数据库链接：

HGNC: 17027

OMIM: 607550

KEGG: hsa:117247

STRING: 9606.ENSP00000357844

UniGene: Hs.591327