SIRPB1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SIRPB1 Polyclonal antibody
Uniprot No.：

O00241
基因名：

SIRPB1
别名：

SIRPB1 antibody; Signal-regulatory protein beta-1 antibody; SIRP-beta-1 antibody; CD172 antigen-like family member B antibody; CD antigen CD172b antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Signal-regulatory protein beta-1 protein (30-371AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
基因功能参考文献：
1. SIRPB1 copy-number polymorphism was significantly associated with impulsive-disinhibited personality scores in a dose-dependent manner. PMID: 25039969
2. SIRPbeta1 is a novel IFN-induced microglial receptor that supports clearance of neural debris and Abeta aggregates by stimulating phagocytosis. PMID: 19893026
3. SIRP beta 1 is a disulfide-linked homodimer in leukocytes that regulates neutrophil transepithelial migration PMID: 16081415
4. This protein has been found differentially expressed in the temporal lobe from patients with schizophrenia. PMID: 19034380
亚细胞定位：

Cell membrane; Single-pass type I membrane protein.
组织特异性：

Detected in monocytes and dendritic cells.
数据库链接：

HGNC: 15928

OMIM: 603889

UniGene: Hs.664861