SEMA6B Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SEMA6B Polyclonal antibody
Uniprot No.：

Q9H3T3
基因名：

SEMA6B
别名：

SEM-SEMA-Y antibody; SEM6B_HUMAN antibody; sema domain; transmembrane domain (TM); and cytoplasmic domain; (semaphorin) 6B antibody; Sema Z antibody; SEMA-VIB antibody; Sema6b antibody; SEMAN antibody; semaphorin VIB antibody; Semaphorin-6B antibody; semaphorin-6Ba antibody; Semaphorin-Z antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Semaphorin-6B protein (756-888AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a cell surface repellent for mossy fibers of developping neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons.; (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium.
基因功能参考文献：
1. Semaphorin 6B is related to tumour differentiation and metastasis in vivo, and tumour cell migration, adhesion and invasion in vitro. PMID: 23781008
2. states a clear relation among breast cancer and SEMA6B expression; moreover we describe for the first time the SEMA6Ba protein and report here the analysis of SEMA6Ba RNA messenger, the protein expression and the cellular localization PMID: 23665584
3. Gene SEMA6B is strongly down regulated by peroxisome proliferator-activated receptors. PMID: 15177567
亚细胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Semaphorin family
组织特异性：

Expressed in the brain in GABAergic neurons.
数据库链接：

HGNC: 10739

OMIM: 608873

KEGG: hsa:10501

STRING: 9606.ENSP00000301293

UniGene: Hs.465642