SCOC Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SCOC Polyclonal antibody
Uniprot No.：

Q9UIL1
基因名：

SCOC
别名：

HRIHFB2072 antibody; Scoc antibody; SCOC_HUMAN antibody; SCOCO antibody; Short coiled coil protein antibody; Short coiled-coil protein antibody; UNC-69 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Short coiled-coil protein (1-121AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Positive regulator of amino acid starvation-induced autophagy.
基因功能参考文献：
1. SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis] PMID: 27023175
2. SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction. PMID: 24098481
3. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process. PMID: 24116125
4. The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037
亚细胞定位：

Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
蛋白家族：

SCOC family
组织特异性：

Widely expressed with highest levels in brain, heart and skeletal muscle.
数据库链接：

HGNC: 20335

KEGG: hsa:60592

STRING: 9606.ENSP00000377751

UniGene: Hs.480815