SCLT1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SCLT1 Polyclonal antibody
Uniprot No.：

Q96NL6
基因名：

SCLT1
别名：

SCLT1 antibody; SAP1 antibody; Sodium channel and clathrin linker 1 antibody; Sodium channel-associated protein 1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Sodium channel and clathrin linker 1 protein (1-79AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization.
基因功能参考文献：
1. study identified 2 cases with a severe ciliopathy phenotype consistent with oro-facio-digital syndrome type IX; the autozygome of each index harbored a single truncating variant and the affected genes (SCLT1 and TBC1D32/C6orf170) have roles in centrosomal biology and ciliogenesis; findings suggest a role of SCLT1 and TBC1D32 in ciliopathy pathogenesis PMID: 24285566
2. Functional study in rat suggests that CAP-1A links clathrin and a sodium channel. PMID: 15797711
亚细胞定位：

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
数据库链接：

HGNC: 26406

OMIM: 611399

KEGG: hsa:132320

STRING: 9606.ENSP00000281142

UniGene: Hs.654690