SBNO2 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody
Uniprot No.：

Q9Y2G9
基因名：

SBNO2
别名：

SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
基因功能参考文献：
1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
蛋白家族：

SBNO family
组织特异性：

Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
数据库链接：

HGNC: 29158

OMIM: 615729

KEGG: hsa:22904

STRING: 9606.ENSP00000354733

UniGene: Hs.408708