RTN4IP1 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RTN4IP1 Polyclonal antibody
Uniprot No.：

Q8WWV3
基因名：

RTN4IP1
别名：

MGC12934 antibody; mitochondrial antibody; NIMP antibody; NOGO interacting mitochondrial protein antibody; NOGO-interacting mitochondrial protein antibody; Reticulon 4 interacting protein 1 antibody; Reticulon 4 interacting protein 1, mitochondrial antibody; Reticulon-4-interacting protein 1 antibody; RT4I1_HUMAN antibody; Rtn4ip1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Reticulon-4-interacting protein 1, mitochondrial protein (41-396AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury.
基因功能参考文献：
1. Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. PMID: 26593267
2. RTN4IP1 has a tumor-suppressive function and may regulate thyroid cancer progression. PMID: 23393170
相关疾病：

Optic atrophy 10 with or without ataxia, mental retardation, and seizures (OPA10)
亚细胞定位：

Mitochondrion outer membrane.
蛋白家族：

Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
组织特异性：

Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
数据库链接：

HGNC: 18647

OMIM: 610502

KEGG: hsa:84816

STRING: 9606.ENSP00000358059

UniGene: Hs.155839