RTKN2 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RTKN2 Polyclonal antibody
Uniprot No.：

Q8IZC4
基因名：

RTKN2
别名：

RTKN2 antibody; PLEKHK1Rhotekin-2 antibody; Pleckstrin homology domain-containing family K member 1 antibody; PH domain-containing family K member 1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Rhotekin-2 protein (1-163AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play an important role in lymphopoiesis.
基因功能参考文献：
1. RTKN2 was upregulated in human bladder cancer tissues and cell lines. Silencing of RTKN2 inhibited proliferation and invasion, and induced cell apoptosis. In addition, knockdown of RTKN2 arrested the cell cycle at the G1 phase via inhibition of the expression of cell cycle-associated proteins. PMID: 27082503
2. RTKN2 was overexpressed in HCC tissues. RTKN2 served an important role in tumorigenesis and metastasis of HCC. PMID: 27081789
3. miR-1246 promotes UVB-induced apoptosis by downregulating RTKN2 expression and that UVB-upregulated miR-1246 released RTKN2-dependent resistance to UVB-induced apoptosis by targeting RTKN2 post-transcriptionally in keratinocyte cells. PMID: 24880483
4. we identified two gene loci associated with rheumatoid arthritis susceptibility- NFKBIE and RTKN2 PMID: 23028356
5. Cloning and characterization of gene expression of rhotekin-2. PMID: 15504364
显示更多

收起更多
组织特异性：

Expressed in lymphocytes, CD4 positive T-cells and bone marrow-derived cells. Also expressed in lung, colon, thymus and brain.
数据库链接：

HGNC: 19364

KEGG: hsa:219790

UniGene: Hs.58559