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  4. RPL26 Antibody, FITC conjugated

RPL26 Antibody, FITC conjugated

说明书
  • 中文名称：
    RPL26兔多克隆抗体, FITC偶联
  • 货号：
    CSB-PA020207LC01HU
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RPL26 Polyclonal antibody
  • Uniprot No.：
    P61254
  • 基因名：
    RPL26
  • 别名：
    tibody; 60S ribosomal protein L26 antibody; 60S ribosomal protein L26 like 1 antibody; DBA11 antibody; FLJ46904 antibody; L26 antibody; OTTHUMP00000135333 antibody; PTB associated splicing factor antibody; Ribosomal protein L26 antibody; Ribosomal protein L26 homolog antibody; Ribosomal protein L26 like 1 antibody; Ribosomal protein L26 pseudogene 1 antibody; RL26_HUMAN antibody; rpl26 antibody; RPL26P1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 60S ribosomal protein L26 protein (48-143AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    FITC
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RPL26 antibodies

RPL26 Proteins

靶点详情

  • 功能：
    Component of the large ribosomal subunit.
  • 基因功能参考文献：
    1. ionizing radiation (IR) inhibits the activity of SMG1, a phosphoinositide-3-kinase-like kinase family member, reducing the binding of SMG1 to a specific region near exon 9 of p53 precursor mRNA and promoting the binding of ribosomal protein L26 (RPL26) to p53 pre-mRNA PMID: 28288992
    2. In colorectal tumor cells RPL26 regulates p73 expression via two distinct mechanisms: protein stability and mRNA translation. PMID: 27825141
    3. Six1 regulates p53 via a dual mechanism involving upregulation of microRNA-27a and downregulation of RPL26. PMID: 26687066
    4. The results showed that knockdown of RPL26 or RPL29 expression significantly suppressed cell proliferation, induced cell arrest at G0/G1 phase and enhanced cell apoptosis PMID: 22868929
    5. Northern Blot Together with RPL5, RPL11, and RPS7, RPL26 is the fourth RP regulating p53 activity that is linked to diamond-blackfan anemia. PMID: 22431104
    6. suggest a model in which the base pairings in the p53 UTR interaction regions are critical for both translational repression and stress induction of p53 by NCL and RPL26 PMID: 22433872
    7. Mdm2 binds L26 and drives its polyubiquitylation and proteasomal degradation. PMID: 18951086

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  • 相关疾病：
    Diamond-Blackfan anemia 11 (DBA11)
  • 蛋白家族：
    Universal ribosomal protein uL24 family
  • 数据库链接：

    HGNC: 10327

    OMIM: 603704

    KEGG: hsa:6154

    STRING: 9606.ENSP00000293842

    UniGene: Hs.482144

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