RMND1 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RMND1 Polyclonal antibody
Uniprot No.：

Q9NWS8
基因名：

RMND1
别名：

bA351K16 antibody; bA351K16.3 antibody; C6orf96 antibody; chromosome 6 open reading frame 96 antibody; FLJ20627 antibody; MGC117362 antibody; MGC149570 antibody; MGC882602 antibody; required for meiotic nuclear division 1 homolog (S. cerevisiae) antibody; Required for meiotic nuclear division protein 1 homolog antibody; Rmnd1 antibody; RMND1_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Required for meiotic nuclear division protein 1 homolog protein (35-160AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
基因功能参考文献：
1. Hearing impairment and renal failure are associated with RMND1 mutations. PMID: 26395190
2. Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] PMID: 26928228
3. Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome. PMID: 23022098
4. The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins. PMID: 23022099
相关疾病：

Combined oxidative phosphorylation deficiency 11 (COXPD11)
亚细胞定位：

Mitochondrion.
蛋白家族：

RMD1/sif2 family
数据库链接：

HGNC: 21176

OMIM: 614917

KEGG: hsa:55005

STRING: 9606.ENSP00000356272

UniGene: Hs.486835