RGS6 Antibody, Biotin conjugated

1. the results suggest that HA117 regulates the development of drug resistance in CT26 cells in vitro and in vivo. PMID: 28731026
2. study shows that HA117 potentially promotes the stem-like signature of the HL60/ATRA cell line by inhibiting by the ubiquitination and degradation of DNMT1 and by down-regulating the expression of the GGL domain of RGS6 PMID: 28665981
3. genetic association studies on a population in Republic of Korea: Data suggest that an SNP in RGS6 (rs2239219) is closely linked to stress-induced abdominal obesity in the population studied. PMID: 28090039
4. Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS6 in fine-tuning TRPC4 activities. PMID: 26987813
5. Our results suggest that HA117 is a strong multidrug resistance gene. PMID: 20635168
6. This suggests that HA117 might be an important resistance gene in pediatric solid tumors. PMID: 23619123
7. No significant association between SNPs of RGS6 and central adiposity has been found. PMID: 26340433
8. reduced RGS6 expression is associated with poor survival in colorectal cancer patients, suggesting that RGS6 expression may serve as an important prognostic marker PMID: 26653562
9. these date demonstrate that RGS6 decreases in tumor tissue and may serve as a novel biomarker for outcomes in pancreatic cancer patients and be a potential therapeutic target potential therapeutic target. PMID: 25120791
10. we found a novel mutation in RGS6, the splice-acceptor variant c.1369-1G>C that was not previously reported in congenital cataract phenotypes. PMID: 25525169
11. genetic association studies in Hispanic-American families in Texas and Colorado: SNP in RGS6 are associated with high dietary fat intake, food preferences, and adiposity/obesity phenotype PMID: 21233807
12. RGS6-induced apoptosis in both breast cancer cells and mouse embryonic fibroblasts does not require its GAP activity toward G proteins PMID: 21041304
13. interacts with SCG10 and promotes neuronal differentiation; role of the G gamma subunit-like (GGL) domain of this protein PMID: 12140291
14. Role of the RGS domain in stress-induced trafficking of RGS6 protein PMID: 12761220
15. RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants PMID: 12761221
16. RGS6 is the first member of the RGS protein family shown to interact with proteins involved in transcriptional regulation. PMID: 14734556

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HGNC: 10002

OMIM: 603894

KEGG: hsa:9628

STRING: 9606.ENSP00000451030

UniGene: Hs.509872