RGS18 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody
Uniprot No.：

Q9NS28
基因名：

RGS18
别名：

Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
基因功能参考文献：
1. These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
2. Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
3. molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
4. gene mapped to chromosome 1. PMID: 16484797
亚细胞定位：

Cytoplasm.
组织特异性：

Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.
数据库链接：

HGNC: 14261

OMIM: 607192

KEGG: hsa:64407

STRING: 9606.ENSP00000356430

UniGene: Hs.440890