REEP3 Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) REEP3 Polyclonal antibody
Uniprot No.：

Q6NUK4
基因名：

REEP3
别名：

REEP3; C10orf74; Receptor expression-enhancing protein 3
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Receptor expression-enhancing protein 3 protein (80-255AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes.
基因功能参考文献：
1. Our results show that REEP3/4 function redundantly to clear the endoplasmic reticulum from metaphase chromatin, thereby ensuring correct progression through mitosis and proper nuclear envelope architecture. PMID: 23911198
2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
3. Receptor Expression-Enhancing Proteins (REEP) 3 is one of the six human homologs of yeast Yop1p, a probable regulator of cellular vesicle trafficking between the endoplasmatic reticulum and the Golgi network. Positional candidate gene for autism. PMID: 17290275
4. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451
5. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 18940312
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亚细胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

DP1 family
组织特异性：

Expressed in circumvallate papillae.
数据库链接：

HGNC: 23711

OMIM: 609348

KEGG: hsa:221035

STRING: 9606.ENSP00000362863

UniGene: Hs.499833